IBS STUDIES

This is a selection of IBS research studies that have come to the attention of IBS Impact from various sources. We encourage researchers who wish to have their studies considered for posting here or on the IBS Impact blog, or to have a listing updated or removed, to email us using the contact links on the home page of this website. On an ongoing or occasional basis, many of the organizations, forums, medical centers and clinical trial databases linked on the Research or Links pages of this site also have listings of open IBS studies that are seeking participants.

 Last update to the IBS Studies page: August 2017

 

Cognitive Mediators of Bowel Discomfort: An Exploratory Study NEW 

Swinburne University of Technology, Hawthorn, Victoria Australia

Do psychological concerns drive your bowel discomfort – help us develop a scale to better measure these processes.
Psychological distress and gastrointestinal symptoms commonly occur together and are frequently reported in community samples. Your responses will help us better understand how thinking patterns impact upon gastrointestinal discomfort. Further your participation will also help us to develop a new scale that can help better identify and target psychological processes associated with gastrointestinal discomfort.  The study involves completing an online questionnaire which should take approximately 60 minutes to complete.

Go into the draw to win 1 of 4 $100AUS Amazon.com vouchers
At the end of the study you are welcome to add your email address (stored independently from the questionnaire data) in order to go into a draw to win 1 of 4 $100AUS Amazon.com vouchers. Winners will be drawn on the 31st of October 2017.

Who can participate?
Anyone over the age of 18 is eligible to participate in the study.
How to participate?
To participate, please click on the link below:
https://swinburnefhad.au1.qualtrics.com/jfe/form/SV_1LK9FqocoRelzCZ

For more information, please contact the research team:
Principal Investigator: Dr Simon Knowles, (03) 9214 8206, email: sknowles@swin.edu.au
Other investigators involved: Dr Pragalathan Apputhurai (Lecturer in Statistics), Dr Rebecca Burgell (Consultant Gastroenterologist, The Alfred Hospital), Ms Sarina Cook (Research Assistant) & Professor Laurie Keefer (Health Psychologist, Susan and Leonard Feinstein IBD Clinical Center, New York).


 Thought Impact Scale Online Study, University of North Carolina/Chapel Hill NEW

Dr. Palsson is a leading international researcher of IBS and its psychological aspects. The current study is not specific to IBS or any other chronic medical condition, and study volunteers need not have a medical condition, but if the Thought Impact Scale is validated through this and other research, it has potential applications for psychological interventions for IBS and other conditions.

Dr. Palsson is seeking adult volunteers aged 18 or over who are fluent in English and reside in the United States to complete two 25 minute surveys 30 days apart. You must be willing to provide him with your first name and an email address so that he can send a participant code number and password, but responses to the surveys themselves are anonymous and cannot be linked in the study database to personally identifying information.

Please address any additional questions or concerns about the study directly to Dr. Palsson at opalsson@med.unc.edu

HOW MUCH DOES YOUR SUBCONSCIOUS MIND INFLUENCE YOU?

Participate in an online research study and get answers to that question.

Dr. Olafur Palsson in the University of North Carolina at Chapel Hill School of Medicine is testing a new questionnaire, called the Thought Impact Scale, which is designed to measure the degree to which subconscious (or non-conscious) mental functions affect people’s conscious behaviors, feelings and life experiences in everyday life. This online study will evaluate how the new questionnaire scores relates to various personal life experiences and characteristics, and assess the reliability and internal consistency of the questionnaire.
Whether you believe you are influenced a lot by your subconscious mind or only a little bit or even not at all, you are invited to participate in this study.

Participation requires:

Completing online surveys twice, about 30 days apart (takes about 25 minutes each time).
Being at least 18 years old, living in the United States and being fluent in English.

In exchange for your participation, you will:

Receive a personal report of your questionnaire results and their meaning. This report will include your scores on the new Thought Impact Scale and other questionnaires used in the study, how those scores compare in general with those of people in the study sample, and what the scores seem to mean about how much connection you have with your subconscious mind and how they relate to other main findings in the study.
Be entered into a drawing for 5 Amazon gift cards of $25 each
Receive a copy of the abstracts of all scientific papers that are published with the findings of this research
http://www.thoughtimpactscale.com


Noisy Guts Project, Marshall Centre, University of Western Australia, Perth NEW

The Marshall Centre, founded by Professor Barry Marshall, Nobel Laureate for his work connecting H. pylori infection to ulcers, is seeking adult volunteers with irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and without gastrointestinal conditions to assist in developing a non-invasive acoustic belt. It is hoped that the belt, which records gut sounds, heart rate, temperature and skin galvanic response, can eventually serve as a tool for the diagnosis of GI disorders.

Commitment includes online screening, consent to confirm diagnosis with one’s physician, one visit to the Marshall Centre for about 2 hours and 40 minutes of wearing the belt, plus provided breakfast, completion of online log of diet and symptoms.  Option to wear the belt home for 24 hours.

For more information, see the following link: http://crowdresearch.uwa.edu.au/project/noisy-guts-project/


Clinical Trial Study for IBS-C in Children

Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7 to 17 Years, With Irritable Bowel Syndrome With Constipation (IBS-C) (LIN-MD-63)

Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C), in children ages 7-17 years. This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 7-11 will receive oral liquid or oral solid capsule and patients 12–17 will receive solid oral capsule formulation. Children ages 7-11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of IBS-C.

Study Population: Male and female patients age 7 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent IBS and for modified Rome III criteria for child/adolescent functional constipation.

Phase: Phase 2

Sponsor: Forest Laboratories

Contact: For more information visit www.marco-polostudies.com or phone 888-609-3456

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Clinical Trial Study for FC in Children

Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children, Ages 6 to 17 Years, Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC) (LIN-MD-62)

Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of functional constipation (FC), in children ages 6-17 years This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 6-11 will receive oral liquid formulation and patients 12–17 will receive solid oral capsule or liquid oral solution. Children ages 6–11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of FC.

Study Population: Male and female patients age 6 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent functional constipation (FC).

Phase: Phase 2

Sponsor: Forest Laboratories

Contact: For more information visit www.marco-polostudies.com or phone 888-609-3456.


 “Impact of IBS on Social Life or Interpersonal Relationships” Online Study.

The Northwestern University Feinberg School of Medicine is seeking adults age 18 years and older with a diagnosis of Irritable Bowel Syndrome (IBS) to participate in a study evaluating patients’ social and interpersonal experiences.

Are you 18 years of age or older with a diagnosis of an IBS? The Center for Psychosocial Research in GI at Northwestern University Feinberg School of Medicine is conducting a research study to better understand the impact IBS may have on your social life or interpersonal relationships, including the role that the attitudes of others may have. This study involves completing several questionnaires about your illness and well-being and should take you about 45 minutes to complete. If you would like to participate, you may do so online by clicking this link:

https://www.surveymonkey.com/s/NUISIBS

Your information will be kept completely anonymous and participation is voluntary. If you have questions about this study, you may contact Dr. Tiffany Taft at ttaft@northwestern.edu.


“Defining the Clinical Features and Prognosis of Post Infectious and Other IBS Groups” Online Survey

The European Gastroenterology Federation is undertaking a survey of patients with irritable bowel syndrome. This is a web based survey designed to help learn more about irritable bowel syndrome in order that physicians might better plan treatments and management. Of particular interest is how symptoms develop over time. The study is multilingual and is currently available in nine languages. To participate, go to www.postinfectious-ibs.eu and click on your language of choice to complete the simple online questionnaire.

 

 

Last update to IBS Studies page August 2017