IBS STUDIES

This is a selection of IBS research studies that have come to the attention of IBS Impact from various sources. We encourage researchers who wish to have their studies considered for posting here or on the IBS Impact blog, or to have a listing updated or removed, to email us using the contact links on the home page of this website. On an ongoing or occasional basis, many of the organizations, forums, medical centers and clinical trial databases linked on the Research or Links pages of this site also have listings of open IBS studies that are seeking participants.

 Last update to the IBS Studies page: May 2016

Clinical Trial Study for IBS-C in Children

Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7 to 17 Years, With Irritable Bowel Syndrome With Constipation (IBS-C) (LIN-MD-63)

Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C), in children ages 7-17 years. This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 7-11 will receive oral liquid or oral solid capsule and patients 12–17 will receive solid oral capsule formulation. Children ages 7-11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of IBS-C.

Study Population: Male and female patients age 7 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent IBS and for modified Rome III criteria for child/adolescent functional constipation.

Phase: Phase 2

Sponsor: Forest Laboratories

Contact: For more information visit www.marco-polostudies.com or phone 888-609-3456

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Clinical Trial Study for FC in Children

Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children, Ages 6 to 17 Years, Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC) (LIN-MD-62)

Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of functional constipation (FC), in children ages 6-17 years This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 6-11 will receive oral liquid formulation and patients 12–17 will receive solid oral capsule or liquid oral solution. Children ages 6–11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of FC.

Study Population: Male and female patients age 6 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent functional constipation (FC).

Phase: Phase 2

Sponsor: Forest Laboratories

Contact: For more information visit www.marco-polostudies.com or phone 888-609-3456.

 

 

 

“Impact of IBS on Social Life or Interpersonal Relationships” Online Study.

The Northwestern University Feinberg School of Medicine is seeking adults age 18 years and older with a diagnosis of Irritable Bowel Syndrome (IBS) to participate in a study evaluating patients’ social and interpersonal experiences.

Are you 18 years of age or older with a diagnosis of an IBS? The Center for Psychosocial Research in GI at Northwestern University Feinberg School of Medicine is conducting a research study to better understand the impact IBS may have on your social life or interpersonal relationships, including the role that the attitudes of others may have. This study involves completing several questionnaires about your illness and well-being and should take you about 45 minutes to complete. If you would like to participate, you may do so online by clicking this link:

https://www.surveymonkey.com/s/NUISIBS

Your information will be kept completely anonymous and participation is voluntary. If you have questions about this study, you may contact Dr. Tiffany Taft at ttaft@northwestern.edu.

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“Defining the Clinical Features and Prognosis of Post Infectious and Other IBS Groups” Online Survey

The European Gastroenterology Federation is undertaking a survey of patients with irritable bowel syndrome. This is a web based survey designed to help learn more about irritable bowel syndrome in order that physicians might better plan treatments and management. Of particular interest is how symptoms develop over time. The study is multilingual and is currently available in nine languages. To participate, go to www.postinfectious-ibs.eu and click on your language of choice to complete the simple online questionnaire.

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Last update to IBS Studies page May 2016