This is a selection of IBS research studies that have come to the attention of IBS Impact from various sources. We encourage researchers who wish to have their studies considered for posting here or on the IBS Impact blog, or to have a listing updated or removed, to email us using the contact form on this website. On an ongoing or occasional basis, many of the organizations, forums, medical centers and clinical trial databases linked on the Research or Links pages of this site also have listings of open IBS studies that are seeking participants.
Last update to the IBS Studies page: November 2017
ContactME-IBS Registry of Potential Volunteers for Research Studies NEW
County Durham and Darlington NHS FoundationTrust, United Kingdom
Seeking adults, 18+ years old, United Kingdom residents only with a diagnosis of irritable bowel syndrome. This registry has been newly launched in September 2017 as part of a 5 year study. If successful, it may be expanded to other locations in the United Kingdom. The registry is designed to assist people with IBS in learning about available research opportunities and assist researchers in recruiting more interested volunteers. As eligibility requirements for different studies vary, it is not a guarantee that a given individual will be contacted for or qualify for a specific study, and there is no obligation to participate in a specific study if offered. You are only expressing interest and giving researchers permission to contact you in the future.
(Note from IBS Impact: As this is a new venture, as of November 2017, portions of the website are still under construction, but we have verified from reputable sources in the IBS community that this is a legitimate opportunity.)
Macquarie University Functional Gastrointestinal Disorder Research Volunteer Registry NEW
Faculties of Human Sciences and Medical and Health Sciences, Sydney, Australia
IBS is the most common condition in the functional gastrointestinal disorder/disorder of gut-brain interaction category. The Macquarie registry is seeking adults, 18+ years old. The registry is designed to assist people with FGIDs in learning about available research opportunities and assist researchers in recruiting more interested volunteers. As eligibility requirements for different studies vary, it is not a guarantee that a given individual will be contacted for or qualify for a specific study, and there is no obligation to participate in a specific study if offered. You are only expressing interest and giving researchers permission to contact you in the future.
Evaluation of Post-Traumatic Stress Disorder in Patients with Inflammatory Bowel Disease, Irritable Bowel Syndrome, and Breast Cancer NEW
Online Study, Northwestern University Department of Gastroenterology and Hepatology
“We are asking you to take part in this research study because we are trying to learn more about the experiences patients living with inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and breast cancer may have with trauma, including post-traumatic stress disorder.”
Seeking adults, 18 or older. Estimated time for completion 45 minutes. Principal investigator: Dr. Tiffany Taft, PsyD. at email@example.com or 312-725-6175.
IBS, Fecal Incontinence and Quality of Life NEW
Online Study, University of Pennsylvania, Hunt Lab, Department of Psychology
Seeking adults 18 or older for anonymous online study. “The purpose of this research is to assess how IBS affects quality of life and determine how many people with IBS have ever experienced fecal incontinence (accidentally passing solid or liquid stool).”
Study contacts: Syed Aajmain, Ife Dawodu, Connie Wong at HuntLabUpenn@gmail.com
Principal Investigator: Dr.Melissa Hunt, PhD at firstname.lastname@example.org
Cognitive Mediators of Bowel Discomfort: An Exploratory Study
Swinburne University of Technology, Hawthorn, Victoria Australia
Do psychological concerns drive your bowel discomfort – help us develop a scale to better measure these processes.
Psychological distress and gastrointestinal symptoms commonly occur together and are frequently reported in community samples. Your responses will help us better understand how thinking patterns impact upon gastrointestinal discomfort. Further your participation will also help us to develop a new scale that can help better identify and target psychological processes associated with gastrointestinal discomfort. The study involves completing an online questionnaire which should take approximately 60 minutes to complete.
Go into the draw to win 1 of 4 $100AUS Amazon.com vouchers
At the end of the study you are welcome to add your email address (stored independently from the questionnaire data) in order to go into a draw to win 1 of 4 $100AUS Amazon.com vouchers. Winners will be drawn on the 31st of October 2017.
Who can participate?
Anyone over the age of 18 is eligible to participate in the study.
How to participate?
To participate, please click on the link below:
For more information, please contact the research team:
Principal Investigator: Dr Simon Knowles, (03) 9214 8206, email: email@example.com
Other investigators involved: Dr Pragalathan Apputhurai (Lecturer in Statistics), Dr Rebecca Burgell (Consultant Gastroenterologist, The Alfred Hospital), Ms Sarina Cook (Research Assistant) & Professor Laurie Keefer (Health Psychologist, Susan and Leonard Feinstein IBD Clinical Center, New York).
Noisy Guts Project, Marshall Centre, University of Western Australia, Perth
The Marshall Centre, founded by Professor Barry Marshall, Nobel Laureate for his work connecting H. pylori infection to ulcers, is seeking adult volunteers with irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and without gastrointestinal conditions to assist in developing a non-invasive acoustic belt. It is hoped that the belt, which records gut sounds, heart rate, temperature and skin galvanic response, can eventually serve as a tool for the diagnosis of GI disorders.
Commitment includes online screening, consent to confirm diagnosis with one’s physician, one visit to the Marshall Centre for about 2 hours and 40 minutes of wearing the belt, plus provided breakfast, completion of online log of diet and symptoms. Option to wear the belt home for 24 hours.
For more information, see the following link: http://crowdresearch.uwa.edu.au/project/noisy-guts-project/
Clinical Trial Study for IBS-C in Children
Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7 to 17 Years, With Irritable Bowel Syndrome With Constipation (IBS-C) (LIN-MD-63)
Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of Irritable Bowel Syndrome with Constipation (IBS-C), in children ages 7-17 years. This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 7-11 will receive oral liquid or oral solid capsule and patients 12–17 will receive solid oral capsule formulation. Children ages 7-11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of IBS-C.
Study Population: Male and female patients age 7 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent IBS and for modified Rome III criteria for child/adolescent functional constipation.
Phase: Phase 2
Sponsor: Forest Laboratories
Clinical Trial Study for FC in Children
Participants Sought for a Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children, Ages 6 to 17 Years, Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC) (LIN-MD-62)
Description: The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of functional constipation (FC), in children ages 6-17 years This study includes up to a 4-week Screening Period, and a 2 to 3-week Pretreatment Period. Patients age 6-11 will receive oral liquid formulation and patients 12–17 will receive solid oral capsule or liquid oral solution. Children ages 6–11 years meeting the entry criteria will be randomized to 1 of 3 doses of linaclotide or placebo for 4 weeks. Children ages 12–17 years meeting the entry criteria will be randomized to 1 of 4 doses of linaclotide or placebo for 4 weeks. This 4-week study will assess the effects of linaclotide on bowel movement frequency, as well as other bowel symptoms of FC.
Study Population: Male and female patients age 6 years to 17 years who meet inclusion criteria, including Rome III symptom criteria for child/adolescent functional constipation (FC).
Phase: Phase 2
Sponsor: Forest Laboratories
“Impact of IBS on Social Life or Interpersonal Relationships” Online Study.
The Northwestern University Feinberg School of Medicine is seeking adults age 18 years and older with a diagnosis of Irritable Bowel Syndrome (IBS) to participate in a study evaluating patients’ social and interpersonal experiences.
Are you 18 years of age or older with a diagnosis of an IBS? The Center for Psychosocial Research in GI at Northwestern University Feinberg School of Medicine is conducting a research study to better understand the impact IBS may have on your social life or interpersonal relationships, including the role that the attitudes of others may have. This study involves completing several questionnaires about your illness and well-being and should take you about 45 minutes to complete. If you would like to participate, you may do so online by clicking this link:
Your information will be kept completely anonymous and participation is voluntary. If you have questions about this study, you may contact Dr. Tiffany Taft at firstname.lastname@example.org.
“Defining the Clinical Features and Prognosis of Post Infectious and Other IBS Groups” Online Survey
The European Gastroenterology Federation is undertaking a survey of patients with irritable bowel syndrome. This is a web based survey designed to help learn more about irritable bowel syndrome in order that physicians might better plan treatments and management. Of particular interest is how symptoms develop over time. The study is multilingual and is currently available in nine languages. To participate, go to www.postinfectious-ibs.eu and click on your language of choice to complete the simple online questionnaire.
Last update to IBS Studies page: November 2017